The length of a lantibiotic hinge region has profound influence on antimicrobial activity and host specificity

Lantibiotics are ribosomally synthesized (methyl)lanthionine containing peptides which can efficiently inhibit the growth of Gram-positive bacteria.As lantibiotics kill bacteria efficiently and resistance to them is difficult to be obtained, they have the potential to be used in many applications, e.g.in pharmaceutical industry or food industry.Nis

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Clinically amyopathic dermatomyositis presenting with isolated facial edema complicated by acute respiratory failure: a case report

Abstract Background In clinically amyopathic dermatomyositis, Swimwear the hallmark cutaneous manifestations are the key to diagnosis.We report a case of clinically amyopathic dermatomyositis which presented with facial edema as the sole cutaneous manifestation and was later complicated by acute respiratory failure leading to death.Case presentatio

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Metabolomic profiling of overnight peritoneal dialysis effluents predicts the peritoneal equilibration test type

Abstract This study primarily aimed to evaluate whether peritoneal equilibration test (PET) results can be predicted through the Artwork metabolomic analysis of overnight peritoneal dialysis (PD) effluents.From a total of 125 patients, overnight PD effluents on the day of the first PET after PD initiation were analyzed.A modified 4.25% dextrose PET

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